Why O'Neil is out? Official report said only Tettey and Wisdom will miss the game surely and Dorrans is in doubt because of his illness.
Anyway I would go for this game with a line up where everyone plays at their best possible position
So if it is 4-4-2 Redmond and Brady on wings and Howson middle. If 4-2-3-1 Hoolahan in the 10 role and Howson on the bench.
I really don't care at the moment about anything else than getting solid display from players and if AN goes again for ridiculous formation lottery I doubt we will get one.
If AN is reading.
Here is your availeable team's best positions
ST/SS: Mbokani, Naismith, Jerome, Bamford
LM/LW - Brady,
RM/RW - Redmond
CAM - Hoolahan,
CM - Howson, Dorrans
DM - Mulumbu, O'Neil
LB - Olsson
RB - Pinto, Whittaker
CB - Klose, Bassong, Bennett, Martin (yes he is bwtter CB than RB, not just good enough)
GK - Ruddy, Rudd
Also formations most players are familiar from previous managers:
4-4-2(with secondary striker or diamond),
4-2-3-1 (wide version)
I hope you go and first pick formation from three availeable and then pick players in the slots by their position. Then just play your game and see if we can fetch result.